HDAC Inhibition with Valproate Improves Direct Cytotoxicity of Monocytes against Mesothelioma Tumor Cells

SIMPLE SUMMARY: Tumor-associated macrophages and monocyte myeloid-derived immunosuppressive cells are associated with bad prognosis in malignant pleural mesothelioma (MPM). This study shows that peripheral blood monocytes can, nevertheless, be cytotoxic for MPM tumor cells. This cytotoxic activity t...

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Detalles Bibliográficos
Autores principales: Hoyos, Clotilde, Fontaine, Alexis, Jacques, Jean-Rock, Heinen, Vincent, Louis, Renaud, Duysinx, Bernard, Scherpereel, Arnaud, Wasielewski, Eric, Jamakhani, Majeed, Hamaidia, Malik, Willems, Luc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100202/
https://www.ncbi.nlm.nih.gov/pubmed/35565292
http://dx.doi.org/10.3390/cancers14092164

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