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Sonic Hedgehog Signaling in Cerebellar Development and Cancer

The sonic hedgehog (SHH) pathway regulates the development of the central nervous system in vertebrates. Aberrant regulation of SHH signaling pathways often causes neurodevelopmental diseases and brain tumors. In the cerebellum, SHH secreted by Purkinje cells is a potent mitogen for granule cell pro...

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Detalles Bibliográficos
Autores principales: Wang, Wanchen, Shiraishi, Ryo, Kawauchi, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100414/
https://www.ncbi.nlm.nih.gov/pubmed/35573667
http://dx.doi.org/10.3389/fcell.2022.864035