Identifying genetic determinants of inflammatory pain in mice using a large-scale gene-targeted screen

Identifying the genetic determinants of pain is a scientific imperative given the magnitude of the global health burden that pain causes. Here, we report a genetic screen for nociception, performed under the auspices of the International Mouse Phenotyping Consortium. A biased set of 110 single-gene...

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Detalles Bibliográficos
Autores principales: Wotton, Janine M., Peterson, Emma, Flenniken, Ann M., Bains, Rasneer S., Veeraragavan, Surabi, Bower, Lynette R., Bubier, Jason A., Parisien, Marc, Bezginov, Alexandr, Haselimashhadi, Hamed, Mason, Jeremy, Moore, Michayla A., Stewart, Michelle E., Clary, Dave A., Delbarre, Daniel J., Anderson, Laura C., D'Souza, Abigail, Goodwin, Leslie O., Harrison, Mark E., Huang, Ziyue, Mckay, Matthew, Qu, Dawei, Santos, Luis, Srinivasan, Subhiksha, Urban, Rachel, Vukobradovic, Igor, Ward, Christopher S., Willett, Amelia M., Braun, Robert E., Brown, Steve D.M., Dickinson, Mary E., Heaney, Jason D., Kumar, Vivek, Lloyd, K.C. Kent, Mallon, Ann-Marie, McKerlie, Colin, Murray, Stephen A., Nutter, Lauryl M.J., Parkinson, Helen, Seavitt, John R., Wells, Sara, Samaco, Rodney C., Chesler, Elissa J., Smedley, Damian, Diatchenko, Luda, Baumbauer, Kyle M., Young, Erin E., Bonin, Robert P., Mandillo, Silvia, White, Jacqueline K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100450/
https://www.ncbi.nlm.nih.gov/pubmed/35552317
http://dx.doi.org/10.1097/j.pain.0000000000002481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100450/
https://www.ncbi.nlm.nih.gov/pubmed/35552317
http://dx.doi.org/10.1097/j.pain.0000000000002481

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