Cargando…
Focused Design of Novel Cyclic Peptides Endowed with GABARAP-Inhibiting Activity
(1) Background: Disfunctions in autophagy machinery have been identified in various conditions, including neurodegenerative diseases, cancer, and inflammation. Among mammalian autophagy proteins, the Atg8 family member GABARAP has been shown to be greatly involved in the autophagy process of prostat...
Autores principales: | Fassi, Enrico Mario Alessandro, Garofalo, Mariangela, Sgrignani, Jacopo, Dei Cas, Michele, Mori, Matteo, Roda, Gabriella, Cavalli, Andrea, Grazioso, Giovanni |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100651/ https://www.ncbi.nlm.nih.gov/pubmed/35563459 http://dx.doi.org/10.3390/ijms23095070 |
Ejemplares similares
-
How Computational Chemistry and Drug Delivery Techniques Can Support the Development of New Anticancer Drugs
por: Garofalo, Mariangela, et al.
Publicado: (2020) -
Mechanistic Insights into the Antibiofilm Mode of Action of Ellagic Acid
por: Ratti, Alessandro, et al.
Publicado: (2023) -
Computational Design and Biological Evaluation of Analogs of Lupin Peptide P5 Endowed with Dual PCSK9/HMG-CoAR Inhibiting Activity
por: Lammi, Carmen, et al.
Publicado: (2022) -
Oxidation State Dependent Conformational Changes of HMGB1 Regulate the Formation of the CXCL12/HMGB1 Heterocomplex
por: Fassi, Enrico M.A., et al.
Publicado: (2019) -
Computational
Design, Synthesis, and Biological Evaluation
of Diimidazole Analogues Endowed with Dual PCSK9/HMG-CoAR-Inhibiting
Activity
por: Lammi, Carmen, et al.
Publicado: (2023)