Acridine Based N-Acylhydrazone Derivatives as Potential Anticancer Agents: Synthesis, Characterization and ctDNA/HSA Spectroscopic Binding Properties

A series of novel acridine N-acylhydrazone derivatives have been synthesized as potential topoisomerase I/II inhibitors, and their binding (calf thymus DNA—ctDNA and human serum albumin—HSA) and biological activities as potential anticancer agents on proliferation of A549 and CCD-18Co have been eval...

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Detalles Bibliográficos
Autores principales: Vilková, Mária, Hudáčová, Monika, Palušeková, Nikola, Jendželovský, Rastislav, Almáši, Miroslav, Béres, Tibor, Fedoročko, Peter, Kožurková, Mária
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100673/
https://www.ncbi.nlm.nih.gov/pubmed/35566236
http://dx.doi.org/10.3390/molecules27092883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100673/
https://www.ncbi.nlm.nih.gov/pubmed/35566236
http://dx.doi.org/10.3390/molecules27092883

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