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Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report

BACKGROUND: There is no consensus on the antithrombotic treatment strategy for patients with coronary artery ectasia (CAE). CASE SUMMARY: This case reports the dynamic observation of a patient for 48 mo after a diagnosis of CAE with acute myocardial infarction (AMI). The first antithrombotic agents...

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Autores principales: Liu, Rui-Feng, Gao, Xiang-Yu, Liang, Si-Wen, Zhao, Hui-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100716/
https://www.ncbi.nlm.nih.gov/pubmed/35647140
http://dx.doi.org/10.12998/wjcc.v10.i12.3936
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author Liu, Rui-Feng
Gao, Xiang-Yu
Liang, Si-Wen
Zhao, Hui-Qiang
author_facet Liu, Rui-Feng
Gao, Xiang-Yu
Liang, Si-Wen
Zhao, Hui-Qiang
author_sort Liu, Rui-Feng
collection PubMed
description BACKGROUND: There is no consensus on the antithrombotic treatment strategy for patients with coronary artery ectasia (CAE). CASE SUMMARY: This case reports the dynamic observation of a patient for 48 mo after a diagnosis of CAE with acute myocardial infarction (AMI). The first antithrombotic agents used were aspirin (100 mg/d) and clopidogrel (75 mg/d). During the sixth month of observation, a second AMI occurred involving the same culprit vessel; therefore, antithrombotic agents were changed to aspirin (100 mg/d) and ticagrelor (90 mg twice per day). Twelve months after the second AMI, an attempt to reduce the dosage ticagrelor failed; therefore the original dose was continued. The CAE was relatively stable during the following 4 years. CONCLUSION: This case indicates that a combination of aspirin and ticagrelor may be more effective for CAE patients with AMI than aspirin and clopidogrel.
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spelling pubmed-91007162022-05-26 Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report Liu, Rui-Feng Gao, Xiang-Yu Liang, Si-Wen Zhao, Hui-Qiang World J Clin Cases Case Report BACKGROUND: There is no consensus on the antithrombotic treatment strategy for patients with coronary artery ectasia (CAE). CASE SUMMARY: This case reports the dynamic observation of a patient for 48 mo after a diagnosis of CAE with acute myocardial infarction (AMI). The first antithrombotic agents used were aspirin (100 mg/d) and clopidogrel (75 mg/d). During the sixth month of observation, a second AMI occurred involving the same culprit vessel; therefore, antithrombotic agents were changed to aspirin (100 mg/d) and ticagrelor (90 mg twice per day). Twelve months after the second AMI, an attempt to reduce the dosage ticagrelor failed; therefore the original dose was continued. The CAE was relatively stable during the following 4 years. CONCLUSION: This case indicates that a combination of aspirin and ticagrelor may be more effective for CAE patients with AMI than aspirin and clopidogrel. Baishideng Publishing Group Inc 2022-04-26 2022-04-26 /pmc/articles/PMC9100716/ /pubmed/35647140 http://dx.doi.org/10.12998/wjcc.v10.i12.3936 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Case Report
Liu, Rui-Feng
Gao, Xiang-Yu
Liang, Si-Wen
Zhao, Hui-Qiang
Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report
title Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report
title_full Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report
title_fullStr Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report
title_full_unstemmed Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report
title_short Antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: A case report
title_sort antithrombotic treatment strategy for patients with coronary artery ectasia and acute myocardial infarction: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100716/
https://www.ncbi.nlm.nih.gov/pubmed/35647140
http://dx.doi.org/10.12998/wjcc.v10.i12.3936
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