Synthesis of Berberine and Canagliflozin Chimera and Investigation into New Antibacterial Activity and Mechanisms

Berberine is an isoquinoline alkaloid isolated from Chinese herbal medicines such as Coptis chinensis. It has many pharmacological actions, such as antibacterial, hypoglycemic, anti-inflammatory, and so on. However, due to the low lipophilicity of berberine, it is difficult to penetrate the bacteria...

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Detalles Bibliográficos
Autores principales: Hao, Wenhui, Che, Shiying, Li, Jinsheng, Luo, Jingyi, Zhang, Wanqiu, Chen, Yang, Zhao, Zijian, Wei, Hao, Xie, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100802/
https://www.ncbi.nlm.nih.gov/pubmed/35566298
http://dx.doi.org/10.3390/molecules27092948

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100802/
https://www.ncbi.nlm.nih.gov/pubmed/35566298
http://dx.doi.org/10.3390/molecules27092948

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