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Hedgehog Signaling Pathway Orchestrates Human Lung Branching Morphogenesis

The Hedgehog (HH) signaling pathway plays an essential role in mouse lung development. We hypothesize that the HH pathway is necessary for branching during human lung development and is impaired in pulmonary hypoplasia. Single-cell, bulk RNA-sequencing data, and human fetal lung tissues were analyze...

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Detalles Bibliográficos
Autores principales:	Belgacemi, Randa, Danopoulos, Soula, Deutsch, Gail, Glass, Ian, Dormoy, Valérian, Bellusci, Saverio, Al Alam, Denise
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100880/ https://www.ncbi.nlm.nih.gov/pubmed/35563656 http://dx.doi.org/10.3390/ijms23095265

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