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Modulation of Mismatch Repair and the SOCS1/p53 Axis by microRNA-155 in the Colon of Patients with Primary Sclerosing Cholangitis

Deficient mismatch repair (MMR) proteins may lead to DNA damage and microsatellite instability. Primary sclerosing cholangitis (PSC) is a risk factor for colitis-associated colon cancer. MiR-155 is suggested to act as a key regulating node, linking inflammation and tumorigenesis. However, its involv...

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Detalles Bibliográficos
Autores principales: Adamowicz, Monika, Stukan, Iga, Milkiewicz, Piotr, Bialek, Andrzej, Milkiewicz, Malgorzata, Kempinska-Podhorodecka, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100906/
https://www.ncbi.nlm.nih.gov/pubmed/35563301
http://dx.doi.org/10.3390/ijms23094905

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