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Elevated Expression of the Immune Checkpoint Ligand CD276 (B7-H3) in Urothelial Carcinoma Cell Lines Correlates Negatively with the Cell Proliferation

The cell surface molecule CD276 (B7-H3) is an immune checkpoint antigen. The elevated expression of CD276 on tumors contributes to the suppression of anti-tumor T-cell responses and correlates with poor prognosis. Methods: The expression of CD276 was explored in vitro on eight urothelial carcinoma c...

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Detalles Bibliográficos
Autores principales:	Harland, Niklas, Maurer, Florian B., Abruzzese, Tanja, Bock, Cornelia, Montes-Mojarro, Ivonne A., Fend, Falko, Aicher, Wilhelm K., Stenzl, Arnulf, Amend, Bastian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100984/ https://www.ncbi.nlm.nih.gov/pubmed/35563359 http://dx.doi.org/10.3390/ijms23094969

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