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Oral Etoposide and Trastuzumab Use for HER2-Positive Metastatic Breast Cancer: A Retrospective Study from the Institut Curie Hospitals
SIMPLE SUMMARY: Oral etoposide (VP16), an inhibitor of topoisomerase-II, has demonstrated clinical activity in metastatic breast cancer (MBC). To our knowledge, oral VP16 combined with trastuzumab (VP16-T) in HER2+ MBC has not been evaluated before. This combination is biologically relevant, as TOP2...
Autores principales: | Chalumeau, Clelia, Carton, Matthieu, Eeckhoutte, Alexandre, Ballet, Stelly, Vincent-Salomon, Anne, Vuagnat, Perrine, Bellesoeur, Audrey, Pierga, Jean-Yves, Stern, Marc-Henri, Bidard, Francois-Clement, Lerebours, Florence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101021/ https://www.ncbi.nlm.nih.gov/pubmed/35565244 http://dx.doi.org/10.3390/cancers14092114 |
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