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Topical Capsaicin in Poly(lactic-co-glycolic)acid (PLGA) Nanoparticles Decreases Acute Itch and Heat Pain

Background: Capsaicin, the hot pepper agent, produces burning followed by desensitization. To treat localized itch or pain with minimal burning, low capsaicin concentrations can be repeatedly applied. We hypothesized that alternatively controlled release of capsaicin from poly(lactic-co-glycolic aci...

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Detalles Bibliográficos
Autores principales: Malewicz, Nathalie M., Rattray, Zahra, Oeck, Sebastian, Jung, Sebastian, Escamilla-Rivera, Vicente, Chen, Zeming, Tang, Xiangjun, Zhou, Jiangbing, LaMotte, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101161/
https://www.ncbi.nlm.nih.gov/pubmed/35563669
http://dx.doi.org/10.3390/ijms23095275