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The Role of E3 Ligase Pirh2 in Disease

The p53-dependent ubiquitin ligase Pirh2 regulates a number of proteins involved in different cancer-associated processes. Targeting the p53 family proteins, Chk2, p27(Kip1), Twist1 and others, Pirh2 participates in such cellular processes as proliferation, cell cycle regulation, apoptosis and cellu...

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Detalles Bibliográficos
Autores principales: Daks, Alexandra, Fedorova, Olga, Parfenyev, Sergey, Nevzorov, Ivan, Shuvalov, Oleg, Barlev, Nickolai A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101203/
https://www.ncbi.nlm.nih.gov/pubmed/35563824
http://dx.doi.org/10.3390/cells11091515