CD44+ and CD133+ Non-Small Cell Lung Cancer Cells Exhibit DNA Damage Response Pathways and Dormant Polyploid Giant Cancer Cell Enrichment Relating to Their p53 Status

Cancer stem cells (CSCs) play a critical role in the initiation, progression and therapy relapse of many cancers including non-small cell lung cancer (NSCLC). Here, we aimed to address the question of whether the FACS-sorted CSC-like (CD44 + &CD133 +) vs. non-CSC (CD44−/CD133− isogenic subpopula...

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Detalles Bibliográficos
Autores principales: Pustovalova, Margarita, Blokhina, Taisia, Alhaddad, Lina, Chigasova, Anna, Chuprov-Netochin, Roman, Veviorskiy, Alexander, Filkov, Gleb, Osipov, Andreyan N., Leonov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101266/
https://www.ncbi.nlm.nih.gov/pubmed/35563313
http://dx.doi.org/10.3390/ijms23094922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101266/
https://www.ncbi.nlm.nih.gov/pubmed/35563313
http://dx.doi.org/10.3390/ijms23094922

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