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The Quasimesenchymal Pancreatic Ductal Epithelial Cell Line PANC-1—A Useful Model to Study Clonal Heterogeneity and EMT Subtype Shifting

SIMPLE SUMMARY: Malignant tumors often escape therapy due to clonal propagation of a subfraction of drug-resistant cancer cells. The underlying phenomenon of intratumoral heterogeneity is driven by epithelial–mesenchymal plasticity (EMP) involving the developmental programs, epithelial–mesenchymal t...

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Detalles Bibliográficos
Autores principales:	Ungefroren, Hendrik, Thürling, Isabel, Färber, Benedikt, Kowalke, Tanja, Fischer, Tanja, De Assis, Leonardo Vinícius Monteiro, Braun, Rüdiger, Castven, Darko, Oster, Henrik, Konukiewitz, Björn, Wellner, Ulrich Friedrich, Lehnert, Hendrik, Marquardt, Jens-Uwe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101310/ https://www.ncbi.nlm.nih.gov/pubmed/35565186 http://dx.doi.org/10.3390/cancers14092057

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