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Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients

Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) share common culprit foods and potential pathophysiological factors. However, how diet may contribute to disease course and whether this differs between both entities is unclear. We therefore investigated the association of dietary...

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Autores principales: de Graaf, Marlijne C. G., Spooren, Corinne E. G. M., Hendrix, Evelien M. B., Hesselink, Martine A. M., Feskens, Edith J. M., Smolinska, Agnieszka, Keszthelyi, Daniel, Pierik, Marieke J., Mujagic, Zlatan, Jonkers, Daisy M. A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101333/
https://www.ncbi.nlm.nih.gov/pubmed/35565912
http://dx.doi.org/10.3390/nu14091945
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author de Graaf, Marlijne C. G.
Spooren, Corinne E. G. M.
Hendrix, Evelien M. B.
Hesselink, Martine A. M.
Feskens, Edith J. M.
Smolinska, Agnieszka
Keszthelyi, Daniel
Pierik, Marieke J.
Mujagic, Zlatan
Jonkers, Daisy M. A. E.
author_facet de Graaf, Marlijne C. G.
Spooren, Corinne E. G. M.
Hendrix, Evelien M. B.
Hesselink, Martine A. M.
Feskens, Edith J. M.
Smolinska, Agnieszka
Keszthelyi, Daniel
Pierik, Marieke J.
Mujagic, Zlatan
Jonkers, Daisy M. A. E.
author_sort de Graaf, Marlijne C. G.
collection PubMed
description Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) share common culprit foods and potential pathophysiological factors. However, how diet may contribute to disease course and whether this differs between both entities is unclear. We therefore investigated the association of dietary indices with intestinal inflammation and gastrointestinal symptoms in both IBD and IBS patients. Food frequency questionnaires from 238 IBD, 261 IBS and 195 healthy controls (HC) were available to calculate the overall diet quality by the Dutch Healthy Diet-Index 2015 (DHD-2015) and its inflammatory potential by the Adapted Dietary Inflammatory Index (ADII). Intestinal inflammation and symptoms were evaluated by faecal calprotectin and the Gastrointestinal Symptom Rating Scale, respectively. The DHD-2015 was lower in IBD and IBS versus HC (p < 0.001), being associated with calprotectin levels in IBD (b = −4.009, p = 0.006), and with abdominal pain (b = −0.012, p = 0.023) and reflux syndrome (b = −0.016, p = 0.004) in IBS. ADII scores were comparable between groups and were only associated with abdominal pain in IBD (b = 0.194, p = 0.004). In this side-by-side comparison, we found a lower diet quality that was differentially associated with disease characteristics in IBD versus IBS patients. Longitudinal studies are needed to further investigate the role of dietary factors in the development of flares and predominant symptoms.
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spelling pubmed-91013332022-05-14 Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients de Graaf, Marlijne C. G. Spooren, Corinne E. G. M. Hendrix, Evelien M. B. Hesselink, Martine A. M. Feskens, Edith J. M. Smolinska, Agnieszka Keszthelyi, Daniel Pierik, Marieke J. Mujagic, Zlatan Jonkers, Daisy M. A. E. Nutrients Article Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) share common culprit foods and potential pathophysiological factors. However, how diet may contribute to disease course and whether this differs between both entities is unclear. We therefore investigated the association of dietary indices with intestinal inflammation and gastrointestinal symptoms in both IBD and IBS patients. Food frequency questionnaires from 238 IBD, 261 IBS and 195 healthy controls (HC) were available to calculate the overall diet quality by the Dutch Healthy Diet-Index 2015 (DHD-2015) and its inflammatory potential by the Adapted Dietary Inflammatory Index (ADII). Intestinal inflammation and symptoms were evaluated by faecal calprotectin and the Gastrointestinal Symptom Rating Scale, respectively. The DHD-2015 was lower in IBD and IBS versus HC (p < 0.001), being associated with calprotectin levels in IBD (b = −4.009, p = 0.006), and with abdominal pain (b = −0.012, p = 0.023) and reflux syndrome (b = −0.016, p = 0.004) in IBS. ADII scores were comparable between groups and were only associated with abdominal pain in IBD (b = 0.194, p = 0.004). In this side-by-side comparison, we found a lower diet quality that was differentially associated with disease characteristics in IBD versus IBS patients. Longitudinal studies are needed to further investigate the role of dietary factors in the development of flares and predominant symptoms. MDPI 2022-05-06 /pmc/articles/PMC9101333/ /pubmed/35565912 http://dx.doi.org/10.3390/nu14091945 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
de Graaf, Marlijne C. G.
Spooren, Corinne E. G. M.
Hendrix, Evelien M. B.
Hesselink, Martine A. M.
Feskens, Edith J. M.
Smolinska, Agnieszka
Keszthelyi, Daniel
Pierik, Marieke J.
Mujagic, Zlatan
Jonkers, Daisy M. A. E.
Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients
title Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients
title_full Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients
title_fullStr Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients
title_full_unstemmed Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients
title_short Diet Quality and Dietary Inflammatory Index in Dutch Inflammatory Bowel Disease and Irritable Bowel Syndrome Patients
title_sort diet quality and dietary inflammatory index in dutch inflammatory bowel disease and irritable bowel syndrome patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101333/
https://www.ncbi.nlm.nih.gov/pubmed/35565912
http://dx.doi.org/10.3390/nu14091945
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