Arginine Methyltransferase PRMT7 Deregulates Expression of RUNX1 Target Genes in T-Cell Acute Lymphoblastic Leukemia

SIMPLE SUMMARY: Approximately 15–25% of acute lymphoblastic leukemias (ALL) originate from T-lineage cells. The prognosis of T-ALL is less favorable than in B-ALL and patients experience more often relapse, which is associated with dismal survival. No established prognostic biomarkers exist for T-AL...

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Detalles Bibliográficos
Autores principales: Oksa, Laura, Mäkinen, Artturi, Nikkilä, Atte, Hyvärinen, Noora, Laukkanen, Saara, Rokka, Anne, Haapaniemi, Pekka, Seki, Masafumi, Takita, Junko, Kauko, Otto, Heinäniemi, Merja, Lohi, Olli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101393/
https://www.ncbi.nlm.nih.gov/pubmed/35565298
http://dx.doi.org/10.3390/cancers14092169

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