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Immunonutrition and SARS-CoV-2 Infection in Children with Obesity
Since the beginning of the SARS-CoV-2 pandemic, there has been much discussion about the role of diet and antiviral immunity in the context of SARS-CoV-2 infection. Intake levels of vitamins D, C, B12, and iron have been demonstrated to be correlated with lower COVID-19 incidence and mortality. Obes...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101404/ https://www.ncbi.nlm.nih.gov/pubmed/35565668 http://dx.doi.org/10.3390/nu14091701 |
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author | D’Auria, Enza Calcaterra, Valeria Verduci, Elvira Ghezzi, Michele Lamberti, Rossella Vizzuso, Sara Baldassarre, Paola Pendezza, Erica Perico, Veronica Bosetti, Alessandra Zuccotti, Gian Vincenzo |
author_facet | D’Auria, Enza Calcaterra, Valeria Verduci, Elvira Ghezzi, Michele Lamberti, Rossella Vizzuso, Sara Baldassarre, Paola Pendezza, Erica Perico, Veronica Bosetti, Alessandra Zuccotti, Gian Vincenzo |
author_sort | D’Auria, Enza |
collection | PubMed |
description | Since the beginning of the SARS-CoV-2 pandemic, there has been much discussion about the role of diet and antiviral immunity in the context of SARS-CoV-2 infection. Intake levels of vitamins D, C, B12, and iron have been demonstrated to be correlated with lower COVID-19 incidence and mortality. Obesity has been demonstrated to be an independent risk for the severity of COVID-19 infection in adults and also in children. This may be due to different mechanisms, mainly including the gut dysbiosis status observed in obese children. Moreover, the existence of a gut–lung axis added new knowledge to on the potential mechanisms by which diet and dietary substances may affect immune function. The aim of this narrative review is to address the intricate inter-relationship between COVID-19, immune function, and obesity-related inflammation and to describe the role of nutrients and dietary patterns in enhancing the immune system. Two ways to fight against COVID-19 disease exist: one with an antiviral response through immune system boosting and another with antioxidants with an anti-inflammatory effect. In the current pandemic situation, the intake of a varied and balanced diet, rich in micronutrients and bioactive compounds including fibers, should be recommended. However, clinical studies conducted on children affected by SARS-CoV-2 infection and comorbidity are warranted. |
format | Online Article Text |
id | pubmed-9101404 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91014042022-05-14 Immunonutrition and SARS-CoV-2 Infection in Children with Obesity D’Auria, Enza Calcaterra, Valeria Verduci, Elvira Ghezzi, Michele Lamberti, Rossella Vizzuso, Sara Baldassarre, Paola Pendezza, Erica Perico, Veronica Bosetti, Alessandra Zuccotti, Gian Vincenzo Nutrients Review Since the beginning of the SARS-CoV-2 pandemic, there has been much discussion about the role of diet and antiviral immunity in the context of SARS-CoV-2 infection. Intake levels of vitamins D, C, B12, and iron have been demonstrated to be correlated with lower COVID-19 incidence and mortality. Obesity has been demonstrated to be an independent risk for the severity of COVID-19 infection in adults and also in children. This may be due to different mechanisms, mainly including the gut dysbiosis status observed in obese children. Moreover, the existence of a gut–lung axis added new knowledge to on the potential mechanisms by which diet and dietary substances may affect immune function. The aim of this narrative review is to address the intricate inter-relationship between COVID-19, immune function, and obesity-related inflammation and to describe the role of nutrients and dietary patterns in enhancing the immune system. Two ways to fight against COVID-19 disease exist: one with an antiviral response through immune system boosting and another with antioxidants with an anti-inflammatory effect. In the current pandemic situation, the intake of a varied and balanced diet, rich in micronutrients and bioactive compounds including fibers, should be recommended. However, clinical studies conducted on children affected by SARS-CoV-2 infection and comorbidity are warranted. MDPI 2022-04-20 /pmc/articles/PMC9101404/ /pubmed/35565668 http://dx.doi.org/10.3390/nu14091701 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review D’Auria, Enza Calcaterra, Valeria Verduci, Elvira Ghezzi, Michele Lamberti, Rossella Vizzuso, Sara Baldassarre, Paola Pendezza, Erica Perico, Veronica Bosetti, Alessandra Zuccotti, Gian Vincenzo Immunonutrition and SARS-CoV-2 Infection in Children with Obesity |
title | Immunonutrition and SARS-CoV-2 Infection in Children with Obesity |
title_full | Immunonutrition and SARS-CoV-2 Infection in Children with Obesity |
title_fullStr | Immunonutrition and SARS-CoV-2 Infection in Children with Obesity |
title_full_unstemmed | Immunonutrition and SARS-CoV-2 Infection in Children with Obesity |
title_short | Immunonutrition and SARS-CoV-2 Infection in Children with Obesity |
title_sort | immunonutrition and sars-cov-2 infection in children with obesity |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101404/ https://www.ncbi.nlm.nih.gov/pubmed/35565668 http://dx.doi.org/10.3390/nu14091701 |
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