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Computational-Based Discovery of the Anti-Cancer Activities of Pyrrole-Based Compounds Targeting the Colchicine-Binding Site of Tubulin

Despite the tubulin-binding agents (TBAs) that are widely used in the clinic for cancer therapy, tumor resistance to TBAs (both inherited and acquired) significantly impairs their effectiveness, thereby decreasing overall survival (OS) and progression-free survival (PFS) rates, especially for the pa...

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Detalles Bibliográficos
Autores principales:	Boichuk, Sergei, Syuzov, Kirill, Bikinieva, Firuza, Galembikova, Aigul, Zykova, Svetlana, Gankova, Ksenia, Igidov, Sergei, Igidov, Nazim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101527/ https://www.ncbi.nlm.nih.gov/pubmed/35566235 http://dx.doi.org/10.3390/molecules27092873

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