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Genetic and Clinical Characteristics of ARID1A Mutated Melanoma Reveal High Tumor Mutational Load without Implications on Patient Survival
SIMPLE SUMMARY: Melanoma is a highly malignant skin cancer with the highest mortality of all cutaneous tumors. Relevant genetic events have been identified, which shape the tumor and also the response to treatment. Recurrent ARID1A mutations have been identified, which are associated with improved o...
Autores principales: | Thielmann, Carl Maximilian, Matull, Johanna, Roth, Sebastian, Placke, Jan-Malte, Chorti, Eleftheria, Zaremba, Anne, Lodde, Georg, Jansen, Philipp, Krefting, Frederik, Kretz, Julia, Möller, Inga, Sucker, Antje, Paschen, Annette, Livingstone, Elisabeth, Zimmer, Lisa, Ugurel, Selma, Schadendorf, Dirk, Hadaschik, Eva, Griewank, Klaus G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101535/ https://www.ncbi.nlm.nih.gov/pubmed/35565222 http://dx.doi.org/10.3390/cancers14092090 |
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