Cargando…

HIV-2 Neutralization Sensitivity in Relation to Co-Receptor Entry Pathways and Env Motifs

HIV-2, compared to HIV-1, elicits potent and broadly neutralizing antibodies, and uses a broad range of co-receptors. However, both sensitivity to neutralization and breadth of co-receptor use varies between HIV-2 isolates, and the molecular background is still not fully understood. Thus, in the cur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Szojka, Zsófia Ilona, Karlson, Sara, Johansson, Emil, Şahin, Gülşen Özkaya, Jansson, Marianne
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101540/ https://www.ncbi.nlm.nih.gov/pubmed/35563157 http://dx.doi.org/10.3390/ijms23094766

Ejemplares similares

Cross-Reactive Antibodies With the Capacity to Mediate HIV-1 Envelope Glycoprotein–Targeted Antibody-Dependent Cellular Cytotoxicity Identified in HIV-2–Infected Individuals
por: Karlsson, Ingrid, et al.
Publicado: (2019)

Automated image-based assay for evaluation of HIV neutralization and cell-to-cell fusion inhibition
por: Sheik-Khalil, Enas, et al.
Publicado: (2014)

Increased Sensitivity to Broadly Neutralizing Antibodies of End-Stage Disease R5 HIV-1 Correlates with Evolution in Env Glycosylation and Charge
por: Borggren, Marie, et al.
Publicado: (2011)

Sequencing the Biology of Entry: The Retroviral env Gene
por: Swanstrom, Ronald, et al.
Publicado: (2017)

Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits
por: Yasmeen, Anila, et al.
Publicado: (2014)

Endocytic Motif on a Biotin-Tagged HIV-1 Env Modulates the Co-Transfer of Env and Gag during Cell-to-Cell Transmission
por: Barría, María Inés, et al.
Publicado: (2021)

Env mutations conferring improved entry efficiency allow HIV to replicate in the presence of IFN
por: Rato, Sylvie, et al.
Publicado: (2013)

Crystal structures of trimeric HIV Env with entry inhibitors BMS-378806 and BMS-626529
por: Pancera, Marie, et al.
Publicado: (2017)

Neutralizing antibodies elicited in rabbits by patient-derived Env trimer immunization
por: Heyndrickx, L, et al.
Publicado: (2012)

The role of polyproline motifs in the histidine kinase EnvZ
por: Motz, Magdalena, et al.
Publicado: (2018)

Structural dynamics reveal isolate-specific differences at neutralization epitopes on HIV Env
por: Hodge, Edgar A., et al.
Publicado: (2022)

Characterizing the Relationship Between Neutralization Sensitivity and env Gene Diversity During ART Suppression
por: Wilson, Andrew, et al.
Publicado: (2021)

Hierarchical Clustering and Trajectory Analyses Reveal Viremia-Independent B-Cell Perturbations in HIV-2 Infection
por: Johansson, Emil, et al.
Publicado: (2022)

Construction of SHIVs expressing quaternary neutralization epitopes in Env and mimicking the neutralization phenotype of typical HIV-1 isolates
por: Theis, JF, et al.
Publicado: (2012)

Recognition and penetration of the HIV-1 Env glycan shield by potent broadly neutralizing antibodies
por: Julien, J, et al.
Publicado: (2012)

An Efficiently Cleaved HIV-1 Clade C Env Selectively Binds to Neutralizing Antibodies
por: Boliar, Saikat, et al.
Publicado: (2015)

Panels of HIV-1 Subtype C Env Reference Strains for Standardized Neutralization Assessments
por: Hraber, Peter, et al.
Publicado: (2017)

Crystal structure, conformational fixation, and entry-related interactions of mature ligand-free HIV-1 Env
por: Kwon, Young Do, et al.
Publicado: (2015)

Analysis of the efficacy of HIV protease inhibitors against SARS-CoV-2′s main protease
por: Mahdi, Mohamed, et al.
Publicado: (2020)

Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike
por: Lee, Jeong Hyun, et al.
Publicado: (2015)

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques
por: Zhao, Fangzhu, et al.
Publicado: (2020)

P04-24. Frequencies of HIV Env-specific B cells and neutralizing antibodies during DNA-prime/protein-boost immunization with three different Env immunogens*
por: Tawde, P, et al.
Publicado: (2009)

Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection
por: Mandizvo, Tawanda, et al.
Publicado: (2022)

Inhibition of HIV-1 Env-Mediated Cell-Cell Fusion by Lectins, Peptide T-20, and Neutralizing Antibodies
por: Yee, Michael, et al.
Publicado: (2011)

Antibody to gp41 MPER Alters Functional Properties of HIV-1 Env without Complete Neutralization
por: Kim, Arthur S., et al.
Publicado: (2014)

High-resolution mapping of the neutralizing and binding specificities of polyclonal sera post-HIV Env trimer vaccination
por: Dingens, Adam S, et al.
Publicado: (2021)

Inhibition Profiling of Retroviral Protease Inhibitors Using an HIV-2 Modular System
por: Mahdi, Mohamed, et al.
Publicado: (2015)

Elicitation of potent serum neutralizing antibody responses in rabbits by immunization with an HIV-1 clade C trimeric Env derived from an Indian elite neutralizer
por: Kumar, Rajesh, et al.
Publicado: (2021)

Selected HIV-1 Env Trimeric Formulations Act as Potent Immunogens in a Rabbit Vaccination Model
por: Heyndrickx, Leo, et al.
Publicado: (2013)

Evolution of Cross-Neutralizing Antibody Specificities to the CD4-BS and the Carbohydrate Cloak of the HIV Env in an HIV-1-Infected Subject
por: Mikell, Iliyana, et al.
Publicado: (2012)

Neutralizing Antibody Responses following Long-Term Vaccination with HIV-1 Env gp140 in Guinea Pigs
por: Bricault, Christine A., et al.
Publicado: (2018)

Glycoengineering HIV-1 Env creates ‘supercharged’ and ‘hybrid’ glycans to increase neutralizing antibody potency, breadth and saturation
por: Crooks, Ema T., et al.
Publicado: (2018)

Peptide Triazole Thiol Irreversibly Inactivates Metastable HIV-1 Env by Accessing Conformational Triggers Intrinsic to Virus–Cell Entry
por: Ang, Charles Gotuaco, et al.
Publicado: (2021)

Envés
por: Amara, Luigi, 1971-
Publicado: (2003)

Pre-Treatment Integrase Inhibitor Resistance and Natural Polymorphisms among HIV-1 Subtype C Infected Patients in Ethiopia
por: Arimide, Dawit Assefa, et al.
Publicado: (2022)

Structural characterization of HIV-1 Env heterotrimers bound to one or two CD4 receptors reveals intermediate Env conformations
por: Dam, Kim-Marie A., et al.
Publicado: (2023)

HIV-1 Tat Promotes Integrin-Mediated HIV Transmission to Dendritic Cells by Binding Env Spikes and Competes Neutralization by Anti-HIV Antibodies
por: Monini, Paolo, et al.
Publicado: (2012)

Daily Sampling of an HIV-1 Patient with Slowly Progressing Disease Displays Persistence of Multiple env Subpopulations Consistent with Neutrality
por: Skar, Helena, et al.
Publicado: (2011)

P19-06. The first hypervariable loop and HIV-1 neutralizing antibodies elicited by gp140 env immunogens
por: Ching, LK, et al.
Publicado: (2009)

Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice
por: McGuire, Andrew T., et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_bjpaae8rsadgi9s20mdci02jpl