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Glycolysis Dependency as a Hallmark of SF3B1-Mutated Cells

SIMPLE SUMMARY: Cancer-associated SF3B1 mutations result in aberrant transcripts whose fate remains unknown. We aimed to investigate the functional consequences of these splice aberrations. Our results show that SF3B1 mutation alters the translation of transcripts encoding proteins involved in metab...

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Detalles Bibliográficos
Autores principales: Vivet-Noguer, Raquel, Tarin, Malcy, Canbezdi, Christine, Dayot, Stephane, Silva, Lisseth, Houy, Alexandre, Martineau, Sylvain, Mieulet, Virginie, Gentric, Géraldine, Loew, Damarys, Lombard, Bérangère, Nemati, Fariba, Richon, Sophie, Guyonnet, Lea, Servois, Vincent, Vagner, Stephan, Stern, Marc-Henri, Roman-Roman, Sergio, Alsafadi, Samar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101609/
https://www.ncbi.nlm.nih.gov/pubmed/35565242
http://dx.doi.org/10.3390/cancers14092113