Cargando…

Insulin-like Growth Factor I Couples Metabolism with Circadian Activity through Hypothalamic Orexin Neurons

Uncoupling of metabolism and circadian activity is associated with an increased risk of a wide spectrum of pathologies. Recently, insulin and the closely related insulin-like growth factor I (IGF-I) were shown to entrain feeding patterns with circadian rhythms. Both hormones act centrally to modulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pignatelli, Jaime, de Sevilla, M. Estrella Fernandez, Sperber, Jacob, Horrillo, Daniel, Medina-Gomez, Gema, Aleman, Ignacio Torres
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101627/ https://www.ncbi.nlm.nih.gov/pubmed/35563069 http://dx.doi.org/10.3390/ijms23094679

Ejemplares similares

Insulin-like growth factor I mitigates post-traumatic stress by inhibiting AMP-kinase in orexin neurons
por: Fernández de Sevilla, M. Estrella, et al.
Publicado: (2022)

Control and coding of pupil size by hypothalamic orexin neurons
por: Grujic, Nikola, et al.
Publicado: (2023)

Odour-induced analgesia mediated by hypothalamic orexin neurons in mice
por: Tashiro, Shogo, et al.
Publicado: (2016)

Circadian and dark-pulse activation of orexin/hypocretin neurons
por: Marston, Oliver J, et al.
Publicado: (2008)

Orexin/Hypocretin and Histamine Cross-Talk on Hypothalamic Neuron Counts in Mice
por: Berteotti, Chiara, et al.
Publicado: (2021)

Targeted Orexin and Hypothalamic Neuropeptides for Migraine
por: Strother, Lauren C., et al.
Publicado: (2018)

Glucokinase inhibitor glucosamine stimulates feeding and activates hypothalamic neuropeptide Y and orexin neurons
por: Zhou, Ligang, et al.
Publicado: (2011)

Hypothalamic Orexin-A Neurons Are Involved in the Response of the Brain Stress System to Morphine Withdrawal
por: Laorden, M. Luisa, et al.
Publicado: (2012)

Lateral Hypothalamic Orexin Neurons Mediate the Reward Effects of Pain Relief Induced by Electroacupuncture
por: Wang, Can, et al.
Publicado: (2022)

The Role of Insulin-like Growth Factor I in Mechanisms of Resilience and Vulnerability to Sporadic Alzheimer’s Disease
por: Zegarra-Valdivia, Jonathan A., et al.
Publicado: (2023)

Circadian regulation of mouse suprachiasmatic nuclei neuronal states shapes responses to orexin
por: Belle, Mino D. C., et al.
Publicado: (2017)

THE REGULATION OF SLEEP AND WAKEFULNESS BY THE HYPOTHALAMIC NEUROPEPTIDE OREXIN/HYPOCRETIN
por: INUTSUKA, AYUMU, et al.
Publicado: (2013)

Cellular activation of hypothalamic hypocretin/orexin neurons facilitates short-term spatial memory in mice
por: Aitta-aho, Teemu, et al.
Publicado: (2016)

PT706. Hypothalamic opioid receptors control feeding behavior though orexin and GABA Neurons
por: Ikeda, Hiroko, et al.
Publicado: (2016)

Circulating Insulin-Like Growth Factor I is Involved in the Effect of High Fat Diet on Peripheral Amyloid β Clearance
por: Herrero-Labrador, Raquel, et al.
Publicado: (2020)

Lateral hypothalamic orexin and melanin-concentrating hormone neurons provide direct input to gonadotropin-releasing hormone neurons in the human
por: Skrapits, Katalin, et al.
Publicado: (2015)

Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons
por: Sousa-Ferreira, Lígia, et al.
Publicado: (2011)

Hypothalamic orexins as possible therapeutic agents in threat and spatial memory disorders
por: Mazur, Filip, et al.
Publicado: (2023)

Dissociating orexin-dependent and -independent functions of orexin neurons using novel Orexin-Flp knock-in mice
por: Chowdhury, Srikanta, et al.
Publicado: (2019)

Recruitment of hypothalamic orexin neurons after formalin injections in adult male rats exposed to a neonatal immune challenge
por: Campbell, Erin J., et al.
Publicado: (2015)

Neural pathways from hypothalamic orexin neurons to the ventrolateral preoptic area mediate sleep impairments induced by conditioned fear
por: Ma, Caifen, et al.
Publicado: (2023)

Circadian actions of orexins on the retinorecipient lateral geniculate complex in rat
por: Chrobok, Lukasz, et al.
Publicado: (2020)

Hippocampus ghrelin signaling mediates appetite through lateral hypothalamic orexin pathways
por: Hsu, Ted M, et al.
Publicado: (2015)

Perifornical Hypothalamic Orexin and Serotonin Modulate the Counterregulatory Response to Hypoglycemic and Glucoprivic Stimuli
por: Otlivanchik, Oleg, et al.
Publicado: (2015)

Awake dynamics and brain-wide direct inputs of hypothalamic MCH and orexin networks
por: González, J. Antonio, et al.
Publicado: (2016)

The orexin neuropeptide system: physical activity and hypothalamic function throughout the aging process
por: Zink, Anastasia N., et al.
Publicado: (2014)

The Anti-tumoral Properties of Orexin/Hypocretin Hypothalamic Neuropeptides: An Unexpected Therapeutic Role
por: Couvineau, Alain, et al.
Publicado: (2018)

Insulin regulates neurovascular coupling through astrocytes
por: Fernandez, Ana M., et al.
Publicado: (2022)

Orexin Neurons Receive Glycinergic Innervations
por: Hondo, Mari, et al.
Publicado: (2011)

Hypothalamic kinin B1 receptor mediates orexin system hyperactivity in neurogenic hypertension
por: Parekh, Rohan Umesh, et al.
Publicado: (2021)

Downregulation of Orexin Receptor in Hypothalamic Paraventricular Nucleus Decreases Blood Pressure in Obese Zucker Rats
por: Zhou, Jing‐Jing, et al.
Publicado: (2019)

The hypothalamic RFamide, QRFP, increases feeding and locomotor activity: The role of Gpr103 and orexin receptors
por: Cook, Chris, et al.
Publicado: (2022)

Choroid plexus function in neurological homeostasis and disorders: The awakening of the circadian clocks and orexins
por: Christensen, Jennaya, et al.
Publicado: (2022)

Frataxin deficiency unveils cell-context dependent actions of insulin-like growth factor I on neurons
por: Franco, Carolina, et al.
Publicado: (2012)

A Relationship between Reduced Nucleus Accumbens Shell and Enhanced Lateral Hypothalamic Orexin Neuronal Activation in Long-Term Fructose Bingeing Behavior
por: Rorabaugh, Jacki M., et al.
Publicado: (2014)

Neurochemical Heterogeneity Among Lateral Hypothalamic Hypocretin/Orexin and Melanin-Concentrating Hormone Neurons Identified Through Single-Cell Gene Expression Analysis
por: Mickelsen, Laura E., et al.
Publicado: (2017)

Still Excited, but Less Aroused—The Effects of Nutritional Ketosis on Epinephrine Response and Hypothalamic Orexin Neuron Activation Following Recurrent Hypoglycemia in Diabetic Rats
por: Nedoboy, Polina E., et al.
Publicado: (2022)

Inhibitory Interplay between Orexin Neurons and Eating
por: González, J. Antonio, et al.
Publicado: (2016)

Activity of putative orexin neurons during cataplexy
por: Zhou, Shi, et al.
Publicado: (2022)

Orexin neurons inhibit sleep to promote arousal
por: De Luca, Roberto, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_vjet6orfltb2a3tjntlc2diil2