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High Dose Local Photon Irradiation Is Crucial in Anti-CTLA-4 Antibody Therapy to Enhance the Abscopal Response in a Murine Pancreatic Carcinoma Model

SIMPLE SUMMARY: Pancreatic cancer is an extremely treatment-resistant neoplasm to chemotherapy and immunotherapy. The combination of photon beam irradiation and anti-CTLA-4 antibody (C4) for the anti-tumor effect enhancement at local and distant tumors (abscopal tumors) was investigated using a panc...

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Detalles Bibliográficos
Autores principales:	Yamamoto, Junya, Takahashi, Yutaka, Minami, Kazumasa, Tamari, Keisuke, Katsuki, Shohei, Takenaka, Wataru, Tatekawa, Shotaro, Hayashi, Kazuhiko, Seo, Yuji, Isohashi, Fumiaki, Ogawa, Kazuhiko, Koizumi, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101709/ https://www.ncbi.nlm.nih.gov/pubmed/35565217 http://dx.doi.org/10.3390/cancers14092087

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