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Spectroscopic Evaluation of the Potential Neurotoxic Effects of a New Candidate for Anti-Seizure Medication—TP-315 during Chronic Administration (In Vivo)

The aim of this study was to investigate the potential neurotoxic effect of the new anti-seizure medication candidate—5-(3-chlorophenyl)-4-hexyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (TP-315), after chronic administration to mice. TP-315 was administered to mice intraperitoneally for 14 days. At 24...

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Detalles Bibliográficos
Autores principales: Krysa, Mikolaj, Makuch-Kocka, Anna, Susniak, Katarzyna, Plech, Tomasz, Andres-Mach, Marta, Zagaja, Mirosław, Sroka-Bartnicka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101731/
https://www.ncbi.nlm.nih.gov/pubmed/35562996
http://dx.doi.org/10.3390/ijms23094607