Cargando…

Low-Dose SARS-CoV-2 S-Trimer with an Emulsion Adjuvant Induced Th1-Biased Protective Immunity

During the sustained COVID-19 pandemic, global mass vaccination to achieve herd immunity can prevent further viral spread and mutation. A protein subunit vaccine that is safe, effective, stable, has few storage restrictions, and involves a liable manufacturing process would be advantageous to distri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liao, Hung-Chun, Wu, Wan-Ling, Chiang, Chen-Yi, Huang, Min-Syuan, Shen, Kuan-Yin, Huang, Yu-Ling, Wu, Suh-Chin, Liao, Ching-Len, Chen, Hsin-Wei, Liu, Shih-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101745/ https://www.ncbi.nlm.nih.gov/pubmed/35563292 http://dx.doi.org/10.3390/ijms23094902

Ejemplares similares

Monoclonal antibody targeting the conserved region of the SARS-CoV-2 spike protein to overcome viral variants
por: Wu, Wan-Ling, et al.
Publicado: (2022)

Degradable emulsion as vaccine adjuvant reshapes antigen-specific immunity and thereby ameliorates vaccine efficacy
por: Huang, Chung-Hsiung, et al.
Publicado: (2016)

Intranasal Vaccination With Recombinant Antigen-FLIPr Fusion Protein Alone Induces Long-Lasting Systemic Antibody Responses and Broad T Cell Responses
por: Hsieh, Ming-Shu, et al.
Publicado: (2021)

Recombinant Trimeric HA Protein Immunogenicity of H5N1 Avian Influenza Viruses and Their Combined Use with Inactivated or Adenovirus Vaccines
por: Lin, Shih-Chang, et al.
Publicado: (2011)

Liposome-based polymer complex as a novel adjuvant: enhancement of specific antibody production and isotype switch
por: Chen, Chia-Hung, et al.
Publicado: (2012)

Recombinant lipidated FLIPr effectively enhances mucosal and systemic immune responses for various vaccine types
por: Hsieh, Ming-Shu, et al.
Publicado: (2023)

Alum Pickering Emulsion as Effective Adjuvant to Improve Malaria Vaccine Efficacy
por: Chen, Qiuting, et al.
Publicado: (2021)

Omicron‐specific mRNA vaccine induced cross‐protective immunity against ancestral SARS‐CoV‐2 infection with low neutralizing antibodies
por: Shen, Kuan‐Yin, et al.
Publicado: (2022)

DNA vaccination induced protective immunity against SARS CoV-2 infection in hamsterss
por: Chai, Kit Man, et al.
Publicado: (2021)

Correction: DNA vaccination induced protective immunity against SARS CoV-2 infection in hamsterss
por: Chai, Kit Man, et al.
Publicado: (2023)

A DNA vaccine candidate delivered by an electroacupuncture machine provides protective immunity against SARS-CoV-2 infection
por: Tzeng, Tsai-Teng, et al.
Publicado: (2022)

Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro
por: Ozorowski, Gabriel, et al.
Publicado: (2018)

Water Soluble Iron-Based Coordination Trimers as Synergistic Adjuvants for Pancreatic Cancer
por: Cordani, Marco, et al.
Publicado: (2021)

Suppression of Vimentin Phosphorylation by the Avian Reovirus p17 through Inhibition of CDK1 and Plk1 Impacting the G2/M Phase of the Cell Cycle
por: Chiu, Hung-Chuan, et al.
Publicado: (2016)

Adjuvant chemotherapy in pathological node-negative non-small cell lung cancer
por: Cheng, Ya-Fu, et al.
Publicado: (2023)

Japanese encephalitis virus replicon-based vaccine expressing enterovirus-71 epitope confers dual protection from lethal challenges
por: Huang, Yi-Ting, et al.
Publicado: (2015)

Induction of Th1 and Th2 in the protection against SARS-CoV-2 through mucosal delivery of an adenovirus vaccine expressing an engineered spike protein
por: Chung, Nai-Hsiang, et al.
Publicado: (2022)

Fast and long-lasting immune response to S-trimer COVID-19 vaccine adjuvanted by PIKA
por: Liu, Yuan, et al.
Publicado: (2021)

Interplay of diverse adjuvants and nanoparticle presentation of native-like HIV-1 envelope trimers
por: Sliepen, Kwinten, et al.
Publicado: (2021)

Oil-in-water emulsion adjuvants for pediatric influenza vaccines: a systematic review and meta-analysis
por: Lin, Yu-Ju, et al.
Publicado: (2020)

A Purified Recombinant Lipopeptide as Adjuvant for Cancer Immunotherapy
por: Song, Ying-Chyi, et al.
Publicado: (2014)

Composite hepatocellular carcinoma and small cell carcinoma with early nodal metastasis: A case report
por: Liu, Yu-Jen, et al.
Publicado: (2017)

Induction of high affinity monoclonal antibodies against SARS-CoV-2 variant infection using a DNA prime-protein boost strategy
por: Chiang, Chen-Yi, et al.
Publicado: (2022)

Real-World Evaluation of Modern Adjuvant Radiotherapy in Women with Stage IB Endometrial Cancer
por: Chen, Jenny Ling-Yu, et al.
Publicado: (2021)

Oral uracil–tegafur compared with intravenous chemotherapy as adjuvant therapy for resected early‐stage non‐small cell lung cancer patients
por: Liang, Sheng‐Kai, et al.
Publicado: (2023)

Type IIb Heat Labile Enterotoxin B Subunit as a Mucosal Adjuvant to Enhance Protective Immunity against H5N1 Avian Influenza Viruses
por: Tang, Neos, et al.
Publicado: (2020)

A Trimeric Lipoprotein Assists in Trimeric Autotransporter Biogenesis in Enterobacteria
por: Grin, Iwan, et al.
Publicado: (2014)

The effect of Pickering emulsion adjuvants on the immune efficacy of the COVID-19 polypeptide vaccine
por: Huang, Zhuanqing, et al.
Publicado: (2023)

Antiviral Activity of Compound L3 against Dengue and Zika Viruses In Vitro and In Vivo
por: Chuang, Fu-Kai, et al.
Publicado: (2020)

Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways
por: Huang, Wei-Ru, et al.
Publicado: (2015)

Correction: Avian Reovirus Protein p17 Functions as a Nucleoporin Tpr Suppressor Leading to Activation of p53, p21 and PTEN and Inactivation of PI3K/AKT/mTOR and ERK Signaling Pathways
por: Huang, Wei-Ru, et al.
Publicado: (2015)

Human Kinase/Phosphatase-Wide RNAi Screening Identified Checkpoint Kinase 2 as a Cellular Factor Facilitating Japanese Encephalitis Virus Infection
por: Chan, Yi-Lin, et al.
Publicado: (2018)

Perturbations of Adjuvant Chemotherapy on Cardiovascular Responses and Exercise Tolerance in Patients with Early-Stage Breast Cancer
por: Lin, Hsin-Fu, et al.
Publicado: (2021)

Comparing Magnetic Resonance Fingerprinting (MRF) and the MAGiC Sequence for Simultaneous T1 and T2 Quantitative Measurements in the Female Pelvis: A Prospective Study
por: Huang, Bo-Syuan, et al.
Publicado: (2023)

Prospective double-blind randomized study on the efficacy and safety of an n-3 fatty acid enriched intravenous fat emulsion in postsurgical gastric and colorectal cancer patients
por: Ma, Cheng-Jen, et al.
Publicado: (2015)

Lesion Site Is the Key Prognostic Factor for Keloid Patients Receiving Surgery With Adjuvant Radiotherapy
por: Chen, Frank, et al.
Publicado: (2022)

Particulate Cell Wall Materials of Lactobacillus acidophilus as Vaccine Adjuvant
por: Lin, Shu-Ching, et al.
Publicado: (2022)

Brevilin A Ameliorates Imiquimod-Induced Psoriasis-like Dermatitis and Reduces Th17 Differentiation in Psoriasis Patients
por: Yen, Ling-Jung, et al.
Publicado: (2022)

GLA-AF, an Emulsion-Free Vaccine Adjuvant for Pandemic Influenza
por: Clegg, Christopher H., et al.
Publicado: (2014)

“World in motion” – emulsion adjuvants rising to meet the pandemic challenges
por: O’Hagan, Derek T., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7lgpfg5dgb3gq6h2dpc3jurmg8