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The Role of Treatment Sequencing with Immune-Checkpoint Inhibitors and BRAF/MEK Inhibitors for Response and Survival of Patients with BRAFV600-Mutant Metastatic Melanoma—A Retrospective, Real-World Cohort Study
SIMPLE SUMMARY: The clinical application of kinase inhibitors and immune-checkpoint inhibitors (CPI) has substantially improved the treatment landscape of melanoma. While BRAF/MEK inhibitors allow for rapid disease control, and CPI can evoke durable tumor responses, primary and secondary resistance...
Autores principales: | Haist, Maximilian, Stege, Henner, Ebner, Ronja, Fleischer, Maria Isabel, Loquai, Carmen, Grabbe, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101790/ https://www.ncbi.nlm.nih.gov/pubmed/35565212 http://dx.doi.org/10.3390/cancers14092082 |
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