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Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach

We evaluated the effectiveness of the Extended Prevalence of Infection in Intensive Care (EPIC) III data collection protocol as an active surveillance tool in the eight Intensive Care Units (ICUs) of the Intensive and Critical Care Department of the University Hospital of Turin. A total of 435 patie...

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Autores principales: Montrucchio, Giorgia, Sales, Gabriele, Catozzi, Giulia, Bosso, Stefano, Scanu, Martina, Vignola, Titty Vita, Costamagna, Andrea, Corcione, Silvia, Urbino, Rosario, Filippini, Claudia, De Rosa, Francesco Giuseppe, Brazzi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101920/
https://www.ncbi.nlm.nih.gov/pubmed/35566606
http://dx.doi.org/10.3390/jcm11092482
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author Montrucchio, Giorgia
Sales, Gabriele
Catozzi, Giulia
Bosso, Stefano
Scanu, Martina
Vignola, Titty Vita
Costamagna, Andrea
Corcione, Silvia
Urbino, Rosario
Filippini, Claudia
De Rosa, Francesco Giuseppe
Brazzi, Luca
author_facet Montrucchio, Giorgia
Sales, Gabriele
Catozzi, Giulia
Bosso, Stefano
Scanu, Martina
Vignola, Titty Vita
Costamagna, Andrea
Corcione, Silvia
Urbino, Rosario
Filippini, Claudia
De Rosa, Francesco Giuseppe
Brazzi, Luca
author_sort Montrucchio, Giorgia
collection PubMed
description We evaluated the effectiveness of the Extended Prevalence of Infection in Intensive Care (EPIC) III data collection protocol as an active surveillance tool in the eight Intensive Care Units (ICUs) of the Intensive and Critical Care Department of the University Hospital of Turin. A total of 435 patients were included in a six-day study over 72 ICU beds. 42% had at least one infection: 69% at one site, 26% at two sites and 5% at three or more sites. ICU-acquired infections were the most common (64%), followed by hospital-associated infections (22%) and community-acquired (20%), considering that each patient may have developed more than one infection type. 72% of patients were receiving at least one antibiotic: 48% for prophylaxis and 52% for treatment. Mortality, the length of ICU and hospital stays were 13%, 14 and 29 days, respectively, being all estimated to be significantly different in patients without and with infection (8% vs. 20%; 4 vs. 20 and 11 vs. 50 (p < 0.001). Our data confirm a high prevalence of infections, sepsis and the use of antimicrobials. The repeated punctual prevalence survey seems an effective method to carry out the surveillance of infections and the use of antimicrobials in the ICU. The use of the European Centre for Disease Prevention and Control (ECDC) definitions and the EPIC III protocol seems strategic to allow comparisons with national and international contexts.
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spelling pubmed-91019202022-05-14 Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach Montrucchio, Giorgia Sales, Gabriele Catozzi, Giulia Bosso, Stefano Scanu, Martina Vignola, Titty Vita Costamagna, Andrea Corcione, Silvia Urbino, Rosario Filippini, Claudia De Rosa, Francesco Giuseppe Brazzi, Luca J Clin Med Article We evaluated the effectiveness of the Extended Prevalence of Infection in Intensive Care (EPIC) III data collection protocol as an active surveillance tool in the eight Intensive Care Units (ICUs) of the Intensive and Critical Care Department of the University Hospital of Turin. A total of 435 patients were included in a six-day study over 72 ICU beds. 42% had at least one infection: 69% at one site, 26% at two sites and 5% at three or more sites. ICU-acquired infections were the most common (64%), followed by hospital-associated infections (22%) and community-acquired (20%), considering that each patient may have developed more than one infection type. 72% of patients were receiving at least one antibiotic: 48% for prophylaxis and 52% for treatment. Mortality, the length of ICU and hospital stays were 13%, 14 and 29 days, respectively, being all estimated to be significantly different in patients without and with infection (8% vs. 20%; 4 vs. 20 and 11 vs. 50 (p < 0.001). Our data confirm a high prevalence of infections, sepsis and the use of antimicrobials. The repeated punctual prevalence survey seems an effective method to carry out the surveillance of infections and the use of antimicrobials in the ICU. The use of the European Centre for Disease Prevention and Control (ECDC) definitions and the EPIC III protocol seems strategic to allow comparisons with national and international contexts. MDPI 2022-04-28 /pmc/articles/PMC9101920/ /pubmed/35566606 http://dx.doi.org/10.3390/jcm11092482 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Montrucchio, Giorgia
Sales, Gabriele
Catozzi, Giulia
Bosso, Stefano
Scanu, Martina
Vignola, Titty Vita
Costamagna, Andrea
Corcione, Silvia
Urbino, Rosario
Filippini, Claudia
De Rosa, Francesco Giuseppe
Brazzi, Luca
Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach
title Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach
title_full Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach
title_fullStr Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach
title_full_unstemmed Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach
title_short Effectiveness of an Active and Continuous Surveillance Program for Intensive Care Units Infections Based on the EPIC III (Extended Prevalence of Infection in Intensive Care) Approach
title_sort effectiveness of an active and continuous surveillance program for intensive care units infections based on the epic iii (extended prevalence of infection in intensive care) approach
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101920/
https://www.ncbi.nlm.nih.gov/pubmed/35566606
http://dx.doi.org/10.3390/jcm11092482
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