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SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil

The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to extra caution in workplaces to avoid the coronavirus disease 2019 (COVID-19). In the occupational environment, SARS-CoV-2 testing is a powerful approach in providing valuable information to detect, monitor,...

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Autores principales: Kuriyama, Sergio N., Farjun, Bruna, Henriques-Santos, Bianca Monteiro, Cabanelas, Adriana, Abrantes, Juliana Lourenço, Gesto, João, Fidalgo-Neto, Antonio A., Souza, Thiago Moreno L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101942/
https://www.ncbi.nlm.nih.gov/pubmed/35572963
http://dx.doi.org/10.3389/fmed.2022.862284
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author Kuriyama, Sergio N.
Farjun, Bruna
Henriques-Santos, Bianca Monteiro
Cabanelas, Adriana
Abrantes, Juliana Lourenço
Gesto, João
Fidalgo-Neto, Antonio A.
Souza, Thiago Moreno L.
author_facet Kuriyama, Sergio N.
Farjun, Bruna
Henriques-Santos, Bianca Monteiro
Cabanelas, Adriana
Abrantes, Juliana Lourenço
Gesto, João
Fidalgo-Neto, Antonio A.
Souza, Thiago Moreno L.
author_sort Kuriyama, Sergio N.
collection PubMed
description The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to extra caution in workplaces to avoid the coronavirus disease 2019 (COVID-19). In the occupational environment, SARS-CoV-2 testing is a powerful approach in providing valuable information to detect, monitor, and mitigate the spread of the virus and preserve productivity. Here a centralized Occupational Health Center provided molecular diagnosis and genomic sequences for companies and industries in Rio de Janeiro, Brazil. From May to August 2021, around 20% of the SARS-CoV-2 positive nasopharyngeal swabs from routinely tested workers were sequenced and reproduced the replacement of Gamma with Delta variant observed in regular surveillance programs. Moreover, as a proof-of-concept on the sensibility of the occupational health genomic surveillance program described here, it was also found: i) the primo-identification of B.1.139 and A.2.5 viral genomes in Brazil and ii) an improved dating of Delta VoC evolution, by identifying earlier cases associated with AY-related genomes. We interpret that SARS-CoV-2 molecular testing of workers, independent of symptom presentation, provides an earlier opportunity to identify variants. Thus, considering the continuous monitoring of SARS-CoV-2 in workplaces, positive samples from occupation health programs should be regarded as essential to improve the knowledge on virus genetic diversity and VoC emergence.
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spelling pubmed-91019422022-05-14 SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil Kuriyama, Sergio N. Farjun, Bruna Henriques-Santos, Bianca Monteiro Cabanelas, Adriana Abrantes, Juliana Lourenço Gesto, João Fidalgo-Neto, Antonio A. Souza, Thiago Moreno L. Front Med (Lausanne) Medicine The emergence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to extra caution in workplaces to avoid the coronavirus disease 2019 (COVID-19). In the occupational environment, SARS-CoV-2 testing is a powerful approach in providing valuable information to detect, monitor, and mitigate the spread of the virus and preserve productivity. Here a centralized Occupational Health Center provided molecular diagnosis and genomic sequences for companies and industries in Rio de Janeiro, Brazil. From May to August 2021, around 20% of the SARS-CoV-2 positive nasopharyngeal swabs from routinely tested workers were sequenced and reproduced the replacement of Gamma with Delta variant observed in regular surveillance programs. Moreover, as a proof-of-concept on the sensibility of the occupational health genomic surveillance program described here, it was also found: i) the primo-identification of B.1.139 and A.2.5 viral genomes in Brazil and ii) an improved dating of Delta VoC evolution, by identifying earlier cases associated with AY-related genomes. We interpret that SARS-CoV-2 molecular testing of workers, independent of symptom presentation, provides an earlier opportunity to identify variants. Thus, considering the continuous monitoring of SARS-CoV-2 in workplaces, positive samples from occupation health programs should be regarded as essential to improve the knowledge on virus genetic diversity and VoC emergence. Frontiers Media S.A. 2022-04-29 /pmc/articles/PMC9101942/ /pubmed/35572963 http://dx.doi.org/10.3389/fmed.2022.862284 Text en Copyright © 2022 Kuriyama, Farjun, Henriques-Santos, Cabanelas, Abrantes, Gesto, Fidalgo-Neto and Souza. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Kuriyama, Sergio N.
Farjun, Bruna
Henriques-Santos, Bianca Monteiro
Cabanelas, Adriana
Abrantes, Juliana Lourenço
Gesto, João
Fidalgo-Neto, Antonio A.
Souza, Thiago Moreno L.
SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil
title SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil
title_full SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil
title_fullStr SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil
title_full_unstemmed SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil
title_short SARS-CoV-2 Molecular Epidemiology Can Be Enhanced by Occupational Health: The Experience of Monitoring Variants of Concern in Workplaces in Rio de Janeiro, Brazil
title_sort sars-cov-2 molecular epidemiology can be enhanced by occupational health: the experience of monitoring variants of concern in workplaces in rio de janeiro, brazil
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101942/
https://www.ncbi.nlm.nih.gov/pubmed/35572963
http://dx.doi.org/10.3389/fmed.2022.862284
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