The Placental NLRP3 Inflammasome and Its Downstream Targets, Caspase-1 and Interleukin-6, Are Increased in Human Fetal Growth Restriction: Implications for Aberrant Inflammation-Induced Trophoblast Dysfunction

Fetal growth restriction (FGR) is commonly associated with placental insufficiency and inflammation. Nonetheless, the role played by inflammasomes in the pathogenesis of FGR is poorly understood. We hypothesised that placental inflammasomes are differentially expressed and contribute to the aberrant...

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Detalles Bibliográficos
Autores principales: Alfian, Irvan, Chakraborty, Amlan, Yong, Hannah E. J., Saini, Sheetal, Lau, Ricky W. K., Kalionis, Bill, Dimitriadis, Evdokia, Alfaidy, Nadia, Ricardo, Sharon D., Samuel, Chrishan S., Murthi, Padma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102093/
https://www.ncbi.nlm.nih.gov/pubmed/35563719
http://dx.doi.org/10.3390/cells11091413

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