Cargando…

Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair

Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiog...

Descripción completa

Detalles Bibliográficos
Autores principales: Pozo Osinalde, Eduardo, Salinas Gallegos, Alejandra, Gordillo, Ximena, Nombela Franco, Luis, Marcos-Alberca, Pedro, Mahía, Patricia, Tirado-Conte, Gabriela, Gómez de Diego, José Juan, Jiménez Quevedo, Pilar, Fernández-Ortíz, Antonio, Pérez-Villacastín, Julián, de Agustín Loeches, Jose Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102104/
https://www.ncbi.nlm.nih.gov/pubmed/35566402
http://dx.doi.org/10.3390/jcm11092276
_version_ 1784707250645893120
author Pozo Osinalde, Eduardo
Salinas Gallegos, Alejandra
Gordillo, Ximena
Nombela Franco, Luis
Marcos-Alberca, Pedro
Mahía, Patricia
Tirado-Conte, Gabriela
Gómez de Diego, José Juan
Jiménez Quevedo, Pilar
Fernández-Ortíz, Antonio
Pérez-Villacastín, Julián
de Agustín Loeches, Jose Alberto
author_facet Pozo Osinalde, Eduardo
Salinas Gallegos, Alejandra
Gordillo, Ximena
Nombela Franco, Luis
Marcos-Alberca, Pedro
Mahía, Patricia
Tirado-Conte, Gabriela
Gómez de Diego, José Juan
Jiménez Quevedo, Pilar
Fernández-Ortíz, Antonio
Pérez-Villacastín, Julián
de Agustín Loeches, Jose Alberto
author_sort Pozo Osinalde, Eduardo
collection PubMed
description Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiogram (TEE) for grading in consecutive transthoracic echocardiogram (TTE) during the follow up. Methods: All the consecutive patients who underwent TEER with MitraClip between 2010 and 2020 in our center were considered. TEE-derived immediate postprocedural MR parameters were reassessed to blindly compare them with follow up MR grading in sequential TTE. Results: We finally included 88 patients (64.8% males; 76 ± 10 years-old). Significant MR was detected in 14.3% of the cases at 6 months, in similar proportion than at postprocedural at 1 month. Among all the intraprocedural TEE quantitative parameters only additive and maximum VC were associated with significant MR persistence. Moreover, on ROC analysis maximum VC demonstrated an excellent discriminatory power (AUC 0.96; p < 0.001) to identify MR ≥ III at 6 months. Thus, a cut-off point of 0.45 cm demonstrated 88% sensitivity and 89% specificity. Conclusion: Among intraprocedural TEE parameters to evaluate residual MR in TEER, maximum and additive VC were the most reliable to predict persistence of significant insufficiency.
format Online
Article
Text
id pubmed-9102104
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-91021042022-05-14 Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair Pozo Osinalde, Eduardo Salinas Gallegos, Alejandra Gordillo, Ximena Nombela Franco, Luis Marcos-Alberca, Pedro Mahía, Patricia Tirado-Conte, Gabriela Gómez de Diego, José Juan Jiménez Quevedo, Pilar Fernández-Ortíz, Antonio Pérez-Villacastín, Julián de Agustín Loeches, Jose Alberto J Clin Med Article Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiogram (TEE) for grading in consecutive transthoracic echocardiogram (TTE) during the follow up. Methods: All the consecutive patients who underwent TEER with MitraClip between 2010 and 2020 in our center were considered. TEE-derived immediate postprocedural MR parameters were reassessed to blindly compare them with follow up MR grading in sequential TTE. Results: We finally included 88 patients (64.8% males; 76 ± 10 years-old). Significant MR was detected in 14.3% of the cases at 6 months, in similar proportion than at postprocedural at 1 month. Among all the intraprocedural TEE quantitative parameters only additive and maximum VC were associated with significant MR persistence. Moreover, on ROC analysis maximum VC demonstrated an excellent discriminatory power (AUC 0.96; p < 0.001) to identify MR ≥ III at 6 months. Thus, a cut-off point of 0.45 cm demonstrated 88% sensitivity and 89% specificity. Conclusion: Among intraprocedural TEE parameters to evaluate residual MR in TEER, maximum and additive VC were the most reliable to predict persistence of significant insufficiency. MDPI 2022-04-19 /pmc/articles/PMC9102104/ /pubmed/35566402 http://dx.doi.org/10.3390/jcm11092276 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Pozo Osinalde, Eduardo
Salinas Gallegos, Alejandra
Gordillo, Ximena
Nombela Franco, Luis
Marcos-Alberca, Pedro
Mahía, Patricia
Tirado-Conte, Gabriela
Gómez de Diego, José Juan
Jiménez Quevedo, Pilar
Fernández-Ortíz, Antonio
Pérez-Villacastín, Julián
de Agustín Loeches, Jose Alberto
Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair
title Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair
title_full Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair
title_fullStr Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair
title_full_unstemmed Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair
title_short Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair
title_sort correlation of intraprocedural and follow up parameters for mitral regurgitation grading after percutaneous edge-to-edge repair
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102104/
https://www.ncbi.nlm.nih.gov/pubmed/35566402
http://dx.doi.org/10.3390/jcm11092276
work_keys_str_mv AT pozoosinaldeeduardo correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT salinasgallegosalejandra correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT gordilloximena correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT nombelafrancoluis correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT marcosalbercapedro correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT mahiapatricia correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT tiradocontegabriela correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT gomezdediegojosejuan correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT jimenezquevedopilar correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT fernandezortizantonio correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT perezvillacastinjulian correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair
AT deagustinloechesjosealberto correlationofintraproceduralandfollowupparametersformitralregurgitationgradingafterpercutaneousedgetoedgerepair