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Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair
Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiog...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102104/ https://www.ncbi.nlm.nih.gov/pubmed/35566402 http://dx.doi.org/10.3390/jcm11092276 |
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author | Pozo Osinalde, Eduardo Salinas Gallegos, Alejandra Gordillo, Ximena Nombela Franco, Luis Marcos-Alberca, Pedro Mahía, Patricia Tirado-Conte, Gabriela Gómez de Diego, José Juan Jiménez Quevedo, Pilar Fernández-Ortíz, Antonio Pérez-Villacastín, Julián de Agustín Loeches, Jose Alberto |
author_facet | Pozo Osinalde, Eduardo Salinas Gallegos, Alejandra Gordillo, Ximena Nombela Franco, Luis Marcos-Alberca, Pedro Mahía, Patricia Tirado-Conte, Gabriela Gómez de Diego, José Juan Jiménez Quevedo, Pilar Fernández-Ortíz, Antonio Pérez-Villacastín, Julián de Agustín Loeches, Jose Alberto |
author_sort | Pozo Osinalde, Eduardo |
collection | PubMed |
description | Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiogram (TEE) for grading in consecutive transthoracic echocardiogram (TTE) during the follow up. Methods: All the consecutive patients who underwent TEER with MitraClip between 2010 and 2020 in our center were considered. TEE-derived immediate postprocedural MR parameters were reassessed to blindly compare them with follow up MR grading in sequential TTE. Results: We finally included 88 patients (64.8% males; 76 ± 10 years-old). Significant MR was detected in 14.3% of the cases at 6 months, in similar proportion than at postprocedural at 1 month. Among all the intraprocedural TEE quantitative parameters only additive and maximum VC were associated with significant MR persistence. Moreover, on ROC analysis maximum VC demonstrated an excellent discriminatory power (AUC 0.96; p < 0.001) to identify MR ≥ III at 6 months. Thus, a cut-off point of 0.45 cm demonstrated 88% sensitivity and 89% specificity. Conclusion: Among intraprocedural TEE parameters to evaluate residual MR in TEER, maximum and additive VC were the most reliable to predict persistence of significant insufficiency. |
format | Online Article Text |
id | pubmed-9102104 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-91021042022-05-14 Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair Pozo Osinalde, Eduardo Salinas Gallegos, Alejandra Gordillo, Ximena Nombela Franco, Luis Marcos-Alberca, Pedro Mahía, Patricia Tirado-Conte, Gabriela Gómez de Diego, José Juan Jiménez Quevedo, Pilar Fernández-Ortíz, Antonio Pérez-Villacastín, Julián de Agustín Loeches, Jose Alberto J Clin Med Article Background: There is no consensus on the best intraprocedural parameter to evaluate residual mitral regurgitation (MR) after transcatheter edge-to-edge mitral repair (TEER). Thus, our aim was to evaluate the predictive value of different MR parameters from intraprocedural transesophageal echocardiogram (TEE) for grading in consecutive transthoracic echocardiogram (TTE) during the follow up. Methods: All the consecutive patients who underwent TEER with MitraClip between 2010 and 2020 in our center were considered. TEE-derived immediate postprocedural MR parameters were reassessed to blindly compare them with follow up MR grading in sequential TTE. Results: We finally included 88 patients (64.8% males; 76 ± 10 years-old). Significant MR was detected in 14.3% of the cases at 6 months, in similar proportion than at postprocedural at 1 month. Among all the intraprocedural TEE quantitative parameters only additive and maximum VC were associated with significant MR persistence. Moreover, on ROC analysis maximum VC demonstrated an excellent discriminatory power (AUC 0.96; p < 0.001) to identify MR ≥ III at 6 months. Thus, a cut-off point of 0.45 cm demonstrated 88% sensitivity and 89% specificity. Conclusion: Among intraprocedural TEE parameters to evaluate residual MR in TEER, maximum and additive VC were the most reliable to predict persistence of significant insufficiency. MDPI 2022-04-19 /pmc/articles/PMC9102104/ /pubmed/35566402 http://dx.doi.org/10.3390/jcm11092276 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Pozo Osinalde, Eduardo Salinas Gallegos, Alejandra Gordillo, Ximena Nombela Franco, Luis Marcos-Alberca, Pedro Mahía, Patricia Tirado-Conte, Gabriela Gómez de Diego, José Juan Jiménez Quevedo, Pilar Fernández-Ortíz, Antonio Pérez-Villacastín, Julián de Agustín Loeches, Jose Alberto Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair |
title | Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair |
title_full | Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair |
title_fullStr | Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair |
title_full_unstemmed | Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair |
title_short | Correlation of Intraprocedural and Follow Up Parameters for Mitral Regurgitation Grading after Percutaneous Edge-to-Edge Repair |
title_sort | correlation of intraprocedural and follow up parameters for mitral regurgitation grading after percutaneous edge-to-edge repair |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102104/ https://www.ncbi.nlm.nih.gov/pubmed/35566402 http://dx.doi.org/10.3390/jcm11092276 |
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