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Relationship between Telomere Length, TERT Genetic Variability and TERT, TP53, SP1, MYC Gene Co-Expression in the Clinicopathological Profile of Breast Cancer

The molecular mechanisms of telomerase reverse transcriptase (TERT) upregulation in breast cancer (BC) are complex. We compared genetic variability within TERT and telomere length with the clinical data of patients with BC. Additionally, we assessed the expression of the TERT, MYC, TP53 and SP1 gene...

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Detalles Bibliográficos
Autores principales: Dratwa, Marta, Wysoczanska, Barbara, Brankiewicz, Wioletta, Stachowicz-Suhs, Martyna, Wietrzyk, Joanna, Matkowski, Rafał, Ekiert, Marcin, Szelachowska, Jolanta, Maciejczyk, Adam, Szajewski, Mariusz, Baginski, Maciej, Bogunia-Kubik, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102200/
https://www.ncbi.nlm.nih.gov/pubmed/35563554
http://dx.doi.org/10.3390/ijms23095164