MicroRNA-449a Inhibits Triple Negative Breast Cancer by Disturbing DNA Repair and Chromatid Separation

Chromosomal instability (CIN) can be a driver of tumorigenesis but is also a promising therapeutic target for cancer associated with poor prognosis such as triple negative breast cancer (TNBC). The treatment of TNBC cells with defects in DNA repair genes with poly(ADP-ribose) polymerase inhibitor (P...

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Detalles Bibliográficos
Autores principales: Vajen, Beate, Bhowmick, Rahul, Greiwe, Luisa, Schäffer, Vera, Eilers, Marlies, Reinkens, Thea, Stalke, Amelie, Schmidt, Gunnar, Fiedler, Jan, Thum, Thomas, DeLuca, David S., Hickson, Ian D., Schlegelberger, Brigitte, Illig, Thomas, Skawran, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102308/
https://www.ncbi.nlm.nih.gov/pubmed/35563522
http://dx.doi.org/10.3390/ijms23095131

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