The distribution and function of GDE2, a regulator of spinal motor neuron survival, are disrupted in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that affects the viability of upper and lower motor neurons. Current options for treatment are limited, necessitating deeper understanding of the mechanisms underlying ALS pathogenesis. Glycerophosphodiester phosphodiesterase 2...

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Detalles Bibliográficos
Autores principales: Westerhaus, Anna, Joseph, Thea, Meyers, Alison J., Jang, Yura, Na, Chan Hyun, Cave, Clinton, Sockanathan, Shanthini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102353/
https://www.ncbi.nlm.nih.gov/pubmed/35550203
http://dx.doi.org/10.1186/s40478-022-01376-x

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