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Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer’s Disease

Amyloid-β (Aβ) accumulation and tauopathy are considered the pathological hallmarks of Alzheimer’s disease (AD), but attenuation in choline signaling, including decreased nicotinic acetylcholine receptors (nAChRs), is evident in the early phase of AD. Currently, there are no drugs that can suppress...

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Detalles Bibliográficos
Autores principales: Takata, Kazuyuki, Kimura, Hiroyuki, Yanagisawa, Daijiro, Harada, Koki, Nishimura, Kaneyasu, Kitamura, Yoshihisa, Shimohama, Shun, Tooyama, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102429/
https://www.ncbi.nlm.nih.gov/pubmed/35566132
http://dx.doi.org/10.3390/molecules27092780