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Nicotinic Acetylcholine Receptors and Microglia as Therapeutic and Imaging Targets in Alzheimer’s Disease
Amyloid-β (Aβ) accumulation and tauopathy are considered the pathological hallmarks of Alzheimer’s disease (AD), but attenuation in choline signaling, including decreased nicotinic acetylcholine receptors (nAChRs), is evident in the early phase of AD. Currently, there are no drugs that can suppress...
Autores principales: | Takata, Kazuyuki, Kimura, Hiroyuki, Yanagisawa, Daijiro, Harada, Koki, Nishimura, Kaneyasu, Kitamura, Yoshihisa, Shimohama, Shun, Tooyama, Ikuo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102429/ https://www.ncbi.nlm.nih.gov/pubmed/35566132 http://dx.doi.org/10.3390/molecules27092780 |
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