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Computational Insight into Biotransformation Profiles of Organophosphorus Flame Retardants to Their Diester Metabolites by Cytochrome P450

Biotransformation of organophosphorus flame retardants (OPFRs) mediated by cytochrome P450 enzymes (CYPs) has a potential correlation with their toxicological effects on humans. In this work, we employed five typical OPFRs including tris(1,3-dichloro-2-propyl) phosphate (TDCIPP), tris(1-chloro-2-pro...

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Detalles Bibliográficos
Autores principales:	Jia, Yue, Yao, Tingji, Ma, Guangcai, Xu, Qi, Zhao, Xianglong, Ding, Hui, Wei, Xiaoxuan, Yu, Haiying, Wang, Zhiguo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102461/ https://www.ncbi.nlm.nih.gov/pubmed/35566150 http://dx.doi.org/10.3390/molecules27092799

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