Case report: A novel cause of acute liver failure in children: A combination of human herpesvirus‐6 infection and homozygous mutation in NBAS gene

Etiologies of acute liver failure in children can be multiple factors including virus infection, drug‐induced damage, and different pathogens. Next‐generation sequencing (NGS) is an emerging method for pan‐pathogen screening. Here we reported a case of acute liver failure in a 15‐month‐old male, usi...

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Detalles Bibliográficos
Autores principales: Cheng, Ying, Xia, Zhi, Huang, Chengjiao, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102514/
https://www.ncbi.nlm.nih.gov/pubmed/35349761
http://dx.doi.org/10.1002/jcla.24343
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author Cheng, Ying
Xia, Zhi
Huang, Chengjiao
Xu, Hui
author_facet Cheng, Ying
Xia, Zhi
Huang, Chengjiao
Xu, Hui
author_sort Cheng, Ying
collection PubMed
description Etiologies of acute liver failure in children can be multiple factors including virus infection, drug‐induced damage, and different pathogens. Next‐generation sequencing (NGS) is an emerging method for pan‐pathogen screening. Here we reported a case of acute liver failure in a 15‐month‐old male, using NGS and gene sequencing to determine the cause of acute liver failure may be caused by pathogens, drug‐induction and pathogenic variant gene.
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spelling pubmed-91025142022-05-18 Case report: A novel cause of acute liver failure in children: A combination of human herpesvirus‐6 infection and homozygous mutation in NBAS gene Cheng, Ying Xia, Zhi Huang, Chengjiao Xu, Hui J Clin Lab Anal Case Report Etiologies of acute liver failure in children can be multiple factors including virus infection, drug‐induced damage, and different pathogens. Next‐generation sequencing (NGS) is an emerging method for pan‐pathogen screening. Here we reported a case of acute liver failure in a 15‐month‐old male, using NGS and gene sequencing to determine the cause of acute liver failure may be caused by pathogens, drug‐induction and pathogenic variant gene. John Wiley and Sons Inc. 2022-03-29 /pmc/articles/PMC9102514/ /pubmed/35349761 http://dx.doi.org/10.1002/jcla.24343 Text en © 2022 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. https://creativecommons.org/licenses/by/4.0/© 2022 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC.This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Cheng, Ying
Xia, Zhi
Huang, Chengjiao
Xu, Hui
Case report: A novel cause of acute liver failure in children: A combination of human herpesvirus‐6 infection and homozygous mutation in NBAS gene
title Case report: A novel cause of acute liver failure in children: A combination of human herpesvirus‐6 infection and homozygous mutation in NBAS gene
title_full Case report: A novel cause of acute liver failure in children: A combination of human herpesvirus‐6 infection and homozygous mutation in NBAS gene
title_fullStr Case report: A novel cause of acute liver failure in children: A combination of human herpesvirus‐6 infection and homozygous mutation in NBAS gene
title_full_unstemmed Case report: A novel cause of acute liver failure in children: A combination of human herpesvirus‐6 infection and homozygous mutation in NBAS gene
title_short Case report: A novel cause of acute liver failure in children: A combination of human herpesvirus‐6 infection and homozygous mutation in NBAS gene
title_sort case report: a novel cause of acute liver failure in children: a combination of human herpesvirus‐6 infection and homozygous mutation in nbas gene
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102514/
https://www.ncbi.nlm.nih.gov/pubmed/35349761
http://dx.doi.org/10.1002/jcla.24343
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