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Inosine monophosphate dehydrogenase type1 sustains tumor growth in hepatocellular carcinoma

BACKGROUND: Inosine monophosphate dehydrogenase (IMPDH) is the key enzyme in the biosynthesis of purine nucleotides. IMPDH1 and IMPDH2 are the two isoforms of IMPDH and they share 84% amino acid similarity and virtually indistinguishable catalytic activity. Although high expression of IMPDH2 has bee...

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Detalles Bibliográficos
Autores principales:	Jia, Xiaoyuan, Liu, Yao, Cheng, Yan, Wang, Yin, Kang, Hui, Ma, Zhongren, Chen, Kan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102537/ https://www.ncbi.nlm.nih.gov/pubmed/35403278 http://dx.doi.org/10.1002/jcla.24416

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