Flavonoid Nobiletin Attenuates Cyclophosphamide-Induced Cystitis in Mice through Mechanisms That Involve Inhibition of IL-1β Induced Connexin 43 Upregulation and Gap Junction Communication in Urothelial Cells

Bladder inflammatory diseases cause various urinary symptoms, such as urinary frequency and painful urination, that impair quality of life. In this study, we used a mouse model of cyclophosphamide (CYP)-induced bladder inflammation and immortalized human urothelial (TRT-HU1) cells to explore the pre...

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Detalles Bibliográficos
Autores principales: Kono, Jin, Ueda, Masakatsu, Sengiku, Atsushi, Suadicani, Sylvia O., Woo, Je Tae, Kobayashi, Takashi, Ogawa, Osamu, Negoro, Hiromitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102543/
https://www.ncbi.nlm.nih.gov/pubmed/35563427
http://dx.doi.org/10.3390/ijms23095037

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