RUMA and RUPCR in children with Henoch–Schonlein purpura

OBJECTIVE: The aim of this study was to compare the qualitative and quantitative targets in the detection of proteinuria in children with HSP. METHODS: Three hundred and forty children were taken as the research subjects. Qualitative and a series of quantitative indicators of urine protein were tested. RESULTS: The qualitative and quantitative of protein in 340 children were analyzed retrospectively. Correlation analysis found that 24hUTP had a strong correlation with age, RUMA, RUPCR, and qualitative urine occult blood (p < 0.01, for all). After regression analysis, RUMA and RUPCR were still significantly correlated with 24hUTP (p < 0.01). At the same time, RUMA and RUPCR had good diagnostic accuracy for proteinuria. When the RUPCR ratio was set as 0.415, the diagnostic sensitivity was 83%, and the specificity was 98.7%. When RUMA was set as 68.215, the sensitivity was 94.3% and the specificity was 96.2%. CONCLUSION: Compared with 24hUTP, RUMA and RUPCR had high sensitivity and specificity for monitoring proteinuria in children with HSP.