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Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells

Heparin is a polysaccharide expressed in animal connective tissue-type mast cells. Owing to the special pentasaccharide sequence, heparin specifically binds to antithrombin (AT) and increases the inhibitory activity of AT towards coagulation enzymes. Heparin isolated from porcine intestinal mucosa h...

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Detalles Bibliográficos
Autores principales: Maccarana, Marco, Jia, Juan, Li, Honglian, Zhang, Xiao, Vlodavsky, Israel, Li, Jin-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102752/
https://www.ncbi.nlm.nih.gov/pubmed/35563215
http://dx.doi.org/10.3390/ijms23094821