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Implications of Heparanase on Heparin Synthesis and Metabolism in Mast Cells
Heparin is a polysaccharide expressed in animal connective tissue-type mast cells. Owing to the special pentasaccharide sequence, heparin specifically binds to antithrombin (AT) and increases the inhibitory activity of AT towards coagulation enzymes. Heparin isolated from porcine intestinal mucosa h...
Autores principales: | Maccarana, Marco, Jia, Juan, Li, Honglian, Zhang, Xiao, Vlodavsky, Israel, Li, Jin-Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102752/ https://www.ncbi.nlm.nih.gov/pubmed/35563215 http://dx.doi.org/10.3390/ijms23094821 |
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