Cargando…
Mcl-1 Differentially Regulates Autophagy in Response to Changes in Energy Status and Mitochondrial Damage
Myeloid cell leukemia-1 (Mcl-1) is a unique antiapoptotic Bcl-2 member that is critical for mitochondrial homeostasis. Recent studies have demonstrated that Mcl-1′s functions extend beyond its traditional role in preventing apoptotic cell death. Specifically, data suggest that Mcl-1 plays a regulato...
Autores principales: | Moyzis, Alexandra G., Lally, Navraj S., Liang, Wenjing, Najor, Rita H., Gustafsson, Åsa B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102819/ https://www.ncbi.nlm.nih.gov/pubmed/35563775 http://dx.doi.org/10.3390/cells11091469 |
Ejemplares similares
-
PINK1 Is Dispensable for Mitochondrial Recruitment of Parkin and Activation of Mitophagy in Cardiac Myocytes
por: Kubli, Dieter A., et al.
Publicado: (2015) -
Aging is associated with a decline in Atg9b‐mediated autophagosome formation and appearance of enlarged mitochondria in the heart
por: Liang, Wenjing, et al.
Publicado: (2020) -
Nuclear Parkin Activates the ERRα Transcriptional Program and Drives Widespread Changes in Gene Expression Following Hypoxia
por: Shires, Sarah E., et al.
Publicado: (2020) -
MCL-1ES Induces MCL-1L-Dependent BAX- and BAK-Independent Mitochondrial Apoptosis
por: Kim, Jae-Hong, et al.
Publicado: (2013) -
Targeting MCL-1 in cancer: current status and perspectives
por: Wang, Haolan, et al.
Publicado: (2021)