Atovaquone: An Inhibitor of Oxidative Phosphorylation as Studied in Gynecologic Cancers

SIMPLE SUMMARY: The Warburg effect in cancer cells (high glucose update and lactate release) is an adaptation that is considered a hallmark of most neoplasms. Blocking oxidative phosphorylation is one way to combat carcinogenesis. Atovaquone is a mitochondrial complex III inhibitor. It is currently...

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Detalles Bibliográficos
Autores principales: Kapur, Arvinder, Mehta, Pooja, Simmons, Aaron D, Ericksen, Spencer S., Mehta, Geeta, Palecek, Sean P., Felder, Mildred, Stenerson, Zach, Nayak, Amruta, Dominguez, Jose Maria Ayuso, Patankar, Manish, Barroilhet, Lisa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102822/
https://www.ncbi.nlm.nih.gov/pubmed/35565426
http://dx.doi.org/10.3390/cancers14092297

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