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Angiotensin II Promotes SARS-CoV-2 Infection via Upregulation of ACE2 in Human Bronchial Cells

Blockers of the renin-angiotensin system (RAS) have been reported to increase the angiotensin converting enzyme (ACE)2, the cellular receptor of SARS-CoV-2, and thus the risk and course of COVID-19. Therefore, we investigated if angiotensin (Ang) II and RAS blockers affected ACE2 expression and SARS...

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Detalles Bibliográficos
Autores principales: Caputo, Ilaria, Caroccia, Brasilina, Frasson, Ilaria, Poggio, Elena, Zamberlan, Stefania, Morpurgo, Margherita, Seccia, Teresa M., Calì, Tito, Brini, Marisa, Richter, Sara N., Rossi, Gian Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9102833/
https://www.ncbi.nlm.nih.gov/pubmed/35563515
http://dx.doi.org/10.3390/ijms23095125