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Open the Technical Black Box of Tumor Mutational Burden (TMB): Factors Affecting Harmonization and Standardization of Panel-Based TMB

As tumor mutational burden (TMB) has been approved as a predictive biomarker for immune checkpoint inhibitors (ICIs), next-generation sequencing (NGS) TMB panels are being increasingly used clinically. However, only a few of them have been validated in clinical trials or authorized by administration...

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Detalles Bibliográficos
Autores principales:	Sung, Meng-Ta, Wang, Yeh-Han, Li, Chien-Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103036/ https://www.ncbi.nlm.nih.gov/pubmed/35563486 http://dx.doi.org/10.3390/ijms23095097

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