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Comparative transcriptome and metabolome analyses reveal the methanol dissimilation pathway of Pichia pastoris
BACKGROUND: Pichia pastoris (Komagataella phaffii) is a model organism widely used for the recombinant expression of eukaryotic proteins, and it can metabolize methanol as its sole carbon and energy source. Methanol is oxidized to formaldehyde by alcohol oxidase (AOX). In the dissimilation pathway,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103059/ https://www.ncbi.nlm.nih.gov/pubmed/35549850 http://dx.doi.org/10.1186/s12864-022-08592-8 |