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Comparative transcriptome and metabolome analyses reveal the methanol dissimilation pathway of Pichia pastoris

BACKGROUND: Pichia pastoris (Komagataella phaffii) is a model organism widely used for the recombinant expression of eukaryotic proteins, and it can metabolize methanol as its sole carbon and energy source. Methanol is oxidized to formaldehyde by alcohol oxidase (AOX). In the dissimilation pathway,...

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Detalles Bibliográficos
Autores principales: Yu, Yi-fan, Yang, Jiashuo, Zhao, Fengguang, Lin, Ying, Han, Shuangyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103059/
https://www.ncbi.nlm.nih.gov/pubmed/35549850
http://dx.doi.org/10.1186/s12864-022-08592-8

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