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Notch2 Blockade Mitigates Methotrexate Chemotherapy-Induced Bone Loss and Marrow Adiposity

Childhood cancer methotrexate (MTX) chemotherapy often causes bone growth impairments, bone loss, and increased risks of fractures during or after treatment, for which the pathobiology is unclear and there is a lack of specific treatment. Our time course analyses of long bones from rats receiving in...

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Detalles Bibliográficos
Autores principales: Peymanfar, Yaser, Su, Yu-Wen, Xian, Cory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9103078/
https://www.ncbi.nlm.nih.gov/pubmed/35563828
http://dx.doi.org/10.3390/cells11091521

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